Fujifilm has patented a method for preparing aqueous solutions with defined pH levels, acids, bases, and additives. The process involves calculating theoretical concentrations, measuring actual pH, generating a mathematical model, and adjusting pH accordingly. This innovative method ensures accurate pH control in solution preparation. GlobalData’s report on Fujifilm gives a 360-degree view of the company including its patenting strategy. Buy the report here.

According to GlobalData’s company profile on Fujifilm, was a key innovation area identified from patents. Fujifilm's grant share as of February 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.

A recently granted patent (Publication Number: US11911712B2) discloses a method for preparing an aqueous solution of a defined pH, involving the use of an acid, a base, and one or more additives. The method includes steps such as calculating theoretical concentrations of acid and base for solutions with different additive concentrations, measuring actual pH values, generating a mathematical model to describe the relationship between pH differences and additive concentrations, and ultimately preparing the desired aqueous solution based on the calculated values. The patent also covers the selection of specific pH values, additive concentrations, and the use of mathematical models to ensure accurate preparation of the aqueous solution.

Furthermore, the patent includes claims related to the apparatus used for implementing the method, which comprises a metering device for feeding the necessary components into a mixing device. The apparatus is designed to calculate theoretical concentrations, generate mathematical models, and control the preparation process based on the defined pH and additive concentrations. Additionally, the apparatus can be integrated with means for carrying out bioprocessing operations such as chromatography, viral inactivation, filtration, and refolding. Overall, the patent provides a detailed and systematic approach for preparing aqueous solutions with precise pH control, ensuring consistency and accuracy in various applications, including bioprocessing operations.

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